US Residents Only

person with HGPS playing the piano

Zokinvy® capsules are taken twice a day with meals, with flexible options to fit the patient’s needs

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Zokinvy is available in 50-mg and 75-mg capsules to provide administration options for starting dosage and maintenance dosing.

50 mg and 75 mg Zokinvy bottles

The contents of Zokinvy can be mixed with Ora-Blend SF® or Ora-Plus®.

  • If the patient cannot access or tolerate Ora-Blend SF or Ora-Plus, you can mix the contents of Zokinvy capsules with orange juice or applesauce

  • Do not mix Zokinvy with any juice containing grapefruit or Seville oranges, also known as bitter oranges

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child with Progeria riding a bicycle

WHAT IS ZOKINVY® (lonafarnib)?

ZOKINVY (zoh-KIN-vee) is a prescription medicine used to treat Hutchinson-Gilford Progeria Syndrome and some types of Progeroid Laminopathies known as processing- deficient Progeroid Laminopathies. These illnesses are caused when the body makes harmful proteins called progerin and progerin-like proteins.

IMPORTANT SAFETY INFORMATION

Do not take ZOKINVY if you are taking:

  • a strong CYP3A inhibitor
  • a strong or moderate CYP3A inducer
  • midazolam
  • lovastatin, simvastatin, or atorvastatin
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